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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
8.18
Human Site:
S2067
Identified Species:
13.85
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S2067
G
F
A
A
L
E
L
S
S
R
H
L
N
V
K
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S2022
G
F
A
A
L
E
L
S
S
R
H
L
N
V
K
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
F1971
I
V
I
L
L
V
V
F
A
L
V
L
H
G
Q
Dog
Lupus familis
XP_547004
2144
235913
L1998
D
N
G
G
F
A
A
L
E
L
N
S
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
E2047
N
G
G
F
A
A
L
E
L
N
S
R
H
L
N
Rat
Rattus norvegicus
XP_001073292
2181
239558
E2035
N
G
G
F
A
A
L
E
L
N
S
R
H
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
T1986
E
L
N
S
R
H
L
T
G
K
S
T
F
S
K
Chicken
Gallus gallus
Q8AV58
2169
239459
N2019
G
F
T
A
L
E
L
N
S
R
H
L
N
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
H1981
E
L
N
S
R
P
V
H
V
K
G
V
F
L
R
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
T1132
E
V
Q
P
S
F
A
T
Q
G
W
F
I
G
V
Fruit Fly
Dros. melanogaster
O97394
2224
246236
G2078
S
V
G
T
L
R
S
G
T
L
G
T
L
G
R
Honey Bee
Apis mellifera
XP_623565
2176
242722
S2014
S
D
L
E
L
Y
R
S
R
Q
G
G
G
G
T
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S2084
S
A
A
N
M
T
R
S
R
E
L
P
T
R
P
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
A2752
V
G
K
S
V
L
E
A
L
C
K
K
D
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
13.3
0
N.A.
6.6
6.6
N.A.
13.3
80
N.A.
0
0
6.6
13.3
13.3
0
P-Site Similarity:
100
100
40
6.6
N.A.
20
20
N.A.
33.3
93.3
N.A.
40
6.6
20
20
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
22
15
22
15
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
22
0
0
8
0
22
8
15
8
8
0
0
0
0
8
% E
% Phe:
0
22
0
15
8
8
0
8
0
0
0
8
15
0
0
% F
% Gly:
22
22
29
8
0
0
0
8
8
8
22
8
8
29
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
22
0
22
8
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
15
8
8
0
0
29
% K
% Leu:
0
15
8
8
43
8
43
8
22
22
8
29
8
22
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
8
15
8
0
0
0
8
0
15
8
0
22
0
15
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
15
8
15
0
15
22
0
15
8
8
15
% R
% Ser:
22
0
0
22
8
0
8
29
22
0
22
8
0
8
0
% S
% Thr:
0
0
8
8
0
8
0
15
8
0
0
15
8
0
8
% T
% Val:
8
22
0
0
8
8
15
0
8
0
8
8
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _